Tetronic and thiotetronic acid derivatives as phospholipase A.su

Details Tetronic and thiotetronic acid derivatives as phospholipase A.su Tetronic and thiotetronic acid derivatives as phospholipase A.su

1991-04-12

1993-09-07

Russell, Mark

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514445, 514826, 549 64, 549 65, 549313, 549314, 549316, 549317, A61K 31365, A61K 3138, C07D30733, C07D33332

Patent

active

052429458

ABSTRACT:
There are disclosed compounds of the formula: ##STR1## wherein X is --CH.sub.2 R;

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L. Reynolds, et al., J. Am. Chem. Soc., "Phospholipose A.sub.2 Inhibition and Modification by Monoalogue," 110, pp. 5172-5177 (1988).
L. Reynolds, et al., J. Biol. Chem., "Inhibition of Venom Phospholipose A.sub.2 by Monolide and Manoalogue," 266 (75), 16512-16517 (1991).
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