Substituted 3-cephem compounds as antibacterial agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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540226, 540227, C07D50120, A61K 31545

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active

052429130

ABSTRACT:
Certain 7-beta-[2-(2-amino-4-thiazolyl)-(Z)-2-(chloromethylene)acetamido]-3-[(subs tituted)methyl]-ceph-3-em-4-carboxylic acids, pharmaceutically-acceptable salts thereof and conventional in vivo hydrolyzable esters thereof are valuable as broad spectrum antibacterial agents, particularly useful for the treatment of bacterial infections in man and other mammals.

REFERENCES:
patent: 4500716 (1985-02-01), Kinast
patent: 4634697 (1987-01-01), Hamashima
patent: 4647658 (1987-03-01), Hamashima
patent: 4912212 (1990-03-01), Ochiai et al.
patent: 4943568 (1990-07-01), Boberg et al.
Chemical Abstracts, vol. 110, 75164(e), 1989.

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