Hydroxyalkyl-substituted-amino-quinolines

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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Details

260286R, 260288R, C07D29508, C07D21542

Patent

active

040353672

ABSTRACT:
Disclosed are compounds of the class of quinolines substituted at the 2-, 3- or 4-position by an amino function bearing a hydroxyalkyl nitrate moiety, e.g. 4-(2-hydroxyethylpiperazino)-quinoline nitrate. The compounds have various pharmacological activities in animals and are useful, for example, as hypotensive and anti-anginal agents. Also disclosed are the corresponding hydroxy intermediates which are useful in preparation of the nitrates and also as hypotensive and anti-anginal agents.

REFERENCES:
patent: 3173918 (1965-03-01), Baget et al.
patent: 3272824 (1966-09-01), Ebetino et al.
patent: 3702849 (1972-11-01), Cronin et al.

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