Mouse monoclonal antibodies specific for normal primate tissue,

Details Mouse monoclonal antibodies specific for normal primate tissue, Mouse monoclonal antibodies specific for normal primate tissue,

1990-10-12

1993-09-07

Lacey, David L.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using tissue cell culture to make a protein or polypeptide

4351722, 4352401, 5303887, 5303888, C12N 1300, C12N 500, A61K 3514

Patent

active

052428133

ABSTRACT:
The subject invention relates to monoclonal antibodies and uses thereof. In particular, the invention relates to three monoclonal antibodies, referred to as B1, B3, and B5, which are useful in the treatment and diagnosis of many forms of cancer.

REFERENCES:
Pastan, et al Cancer Research 51:3781-3787 '91.
Abe, et al JBL 258(19): 11793-11797 '83.
Fine et al., J. Invest. Dermatol., 92(16):825-830 (1989).
Hellstrom et al., Cancer Res., 50:2183-22190 (1990).
Osborne et al., J. Invest. Dermatol., 85:385-388 (1985).
Pastan et al., Cell, 47:641-648 (1986).
Hamilton et al., Cancer Res., 43:5379-5389 (1983).
Bast et al., J. Clin. Invest., 68:1331-1337 (1991).

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