Activated matrix and method of activation

Details Activated matrix and method of activation Activated matrix and method of activation

1980-03-10

1982-05-18

Marquis, Melvyn I.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

65 301, 65 602, 65 603, 260112R, 2601125R, 521 50, 525375, 536 32, 536 43, 536 44, 536 48, 536 49, 536 50, 536110, 536 51, 536 52, 536115, 536107, 536108, 525 543, 525281, 525256, 525257, 525259, 523209, C08L 100

Patent

active

043304400

ABSTRACT:
The invention relates to the carbonylation of cross linked substituted and unsubstituted polysaccharides, their copolymers with macroporous synthetic polymers, macroporous synthetic polymers and rigid supports with pendant hydroxyalkyl groups. The carbonylated product can be used to prepare an affinity chromatography matrix which remains an uncharged species at varying pH's. The carbonylated product is also useful for the preparation of other compounds: Typical polysaccharides are agarose, starch, dextran, cellulose and regenerated cellulose, typical macroporous synthetic polymers are acrylamides, acrylates and methacrylates, typical rigid supports are silica beads coated with hydroxy alkyl groups and typical cabonylating agents are N,N'-carbonyl diimidazole; N,N'carbonyl di-1,2,3-benzotriazole; and N,N'-carbonyl di-1,2,4-triazole.

REFERENCES:
patent: 4211865 (1980-07-01), Ferruti et al.
patent: 4224439 (1980-09-01), Ayers et al.

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