Cephalosporin quinolinium betaines

Details Cephalosporin quinolinium betaines Cephalosporin quinolinium betaines

1981-09-08

1983-08-02

Coughlan, Jr., Paul M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544 22, A61K 31545, C07D50146

Patent

active

043966209

ABSTRACT:
Broad spectrum cephalosporin antibiotics represented by the formula ##STR1## wherein R' is a heterocyclic, eg. 2-aminothizol-4-yl or 5-amino-1,2,4-thiadiazol-3-yl; R" is C.sub.1 -C.sub.4 alkyl, a carboxy-substituted alkyl or cycloalkyl group, or an N-substituted carbamoyl group; and R.sub.1 and R.sub.2 represent substituent groups, eg. amino, hydroxy, halogen, carboxy, carbamoyl, alkyl, alkylamino, sulfo, and sulfonamido; and formulations of the antibiotics are provided. The antibiotics are useful in a method for treating bacterial infections.

REFERENCES:
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patent: 4152432 (1979-05-01), Heymes et al.
patent: 4160830 (1979-07-01), Morimoto et al.
patent: 4200575 (1980-04-01), Numata et al.
patent: 4260747 (1981-04-01), Heymes et al.
patent: 4264595 (1981-04-01), Numata et al.
patent: 4278793 (1981-07-01), Durckheimer et al.

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