Silicone elastomer transdermal matrix system

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

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424449, A61K 970

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active

048141739

ABSTRACT:
A composition for the transmembranal, including transdermal administration of a pharmaceutical preparation comprising medical grade dimethylsiloxane, a catalyst capable of forming an elastomer, a permeation enhancer and a biologically active material, as well as a device for administering the aforementioned compositions and also a method for administering transdermally to a mammal an effective amount of the aforementioned compositions is herein described.

REFERENCES:
patent: 3993073 (1976-11-01), Zaffaroni
patent: 4460371 (1984-07-01), Abber
patent: 4472372 (1984-09-01), Keith et al.
patent: 4559054 (1985-12-01), Bruck
patent: 4592753 (1986-06-01), Panoz
patent: 4601893 (1986-06-01), Cardinal
patent: 4696974 (1987-09-01), Sulc et al.
U.S. patent application Ser. No. 900,865, filed Aug. 27, 1986, M. Mahjour, et al.

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