Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1987-10-26
1990-03-06
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
A61K 3700
Patent
active
049066153
ABSTRACT:
A method for inhibiting the action of enkephalinases in a mannal to thereby elicit an analgesic effect in said mammal is described.
Novel compounds and compositions useful for accomplishing the method of the invention are also described.
REFERENCES:
patent: 3839315 (1974-10-01), Ondetti et al.
patent: 4187216 (1980-02-01), Hassall et al.
patent: 4261884 (1981-04-01), Stammer
patent: 4276288 (1981-06-01), Etschenberg et al.
patent: 4285935 (1981-08-01), Etschenberg et al.
patent: 4385051 (1983-05-01), Oka et al.
patent: 4462943 (1984-07-01), Petrillo, Jr. et al.
patent: 4470973 (1984-09-01), Natarajan et al.
patent: 4472383 (1984-09-01), Oka
patent: 4474692 (1984-10-01), Oka et al.
Biol. Abast., vol. 75, (1983), 36354.
Roques, et al., Nature, 288, (1980), 286.
Chem. Abstr., vol. 101, (1984), 231035k.
Chem. Abstr., vol. 86, (1977), 73101u.
H. Weiner, et al., J.A.C.S., 88, 1966, 3851-3859.
Rich, et al., JCS. Chem. Commun., 1974, 897-898.
Chem. Abstr., 72, 1970, 83014.
Riordan, et al., Tetrahedron Letters, No. 16, 1247-1250, (1976).
Doherty, et al., J. Biol. Chem., (1942), 617-637.
Benoiton, et al., J. Chem. Society, (London), 1964, 824-836.
Mumford et al., "Inhibition of Porcine . . . ", Biochemical and Biophysical Research Communications, vol. 109, No. 4, pp. 1303-1309, (Dec. 31, 1982).
Lee, Jr. Warrick E.
Nelson James R.
Phillips Delbert R.
Schering Corporation
LandOfFree
Substituted dipeptides as inhibitors of enkephalinases does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substituted dipeptides as inhibitors of enkephalinases, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted dipeptides as inhibitors of enkephalinases will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-47519