Process for producing L-tryptophan

Details Process for producing L-tryptophan Process for producing L-tryptophan

1993-11-05

1995-09-05

Stone, Jacqueline M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

4351723, 43525232, 4353201, C12P 1322, C12N 1577

Patent

active

054478570

ABSTRACT:
L-tryptophan is produced by constructing a recombinant DNA composed of a vector DNA and DNA fragments bearing all of genetic information relating to the synthesis of DS, AS, PRT, PRAI, InGPS, TS and PGDH, introducing the recombinant DNA into a microorganism belonging to the genus Corynebacterium or Brevibacterium, culturing the microorganism in a medium, and recovering L-tryptophan accumulated in the culture.

REFERENCES:
patent: 4371614 (1983-02-01), Andeson et al.
patent: 5034318 (1991-07-01), Miwa et al.
Matsui et al., 1988, Agric. Biol. Chem., 52(71:1863-1865.
Somerville, 1983, In: Amino Acids; Biosynthesis and Regulation, Addison-Wesley, Hefmann et al. (eds), pp. 351-361.
Stauffer, 1983, In: Amino Acids: Biosynthesis and Regulation, Addison-Wesley, Hermann et al (eds), pp.103-113.

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