Method and means for detection of arterial lesions

Details Method and means for detection of arterial lesions Method and means for detection of arterial lesions

1985-09-11

1987-04-28

Howell, Kyle L.

Surgery

Truss

Pad

A61B 600

Patent

active

046605630

ABSTRACT:
The atherosclerotic plaques which form arterial lesions have been found to take up lipoproteins from the blood flowing through the arteries. Accordingly, the early detection of arterial disease is accomplished by preparing an infusate composed of radiolabeled low-density lipoproteins and introducing the infusate into the patient's arterial system. A gamma radiation detector is then used to detect and quantify concentrations of the radiolabeled proteins thereby to indicate the locations and sizes of the lesions.

REFERENCES:
patent: 4343734 (1982-08-01), Lian et al.
patent: 4359453 (1982-11-01), Gordon
Hohne, K. H., Digital Image Processing Proceedings, Hamburg, 10-5-1981, Springer-Verlag, Berlin, Hamburg, N.Y., 1981.
Roberts, A. B. et al, "LDLs Concentrate in Damaged Arterial Wall", 53rd Scientific Sessions, Nov. 17-20, 1980, Miami Beach, Fla.
Wilhelmsen, Lars, "Fibrinogen as Risk Factor for Stroke and MI", NEJM, vol. 311, No. 8, Aug. 23, 1984.
Yano, Y. et al, "Myocardial Uptake Studies with 124 Cs and the Scintillation Camera", J. Nucl. Med. (USA) vol. 11, No. 11, Nov. 1970.

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