Process for the preparation of imidazo [1,2-a] pyridines

Details Process for the preparation of imidazo [1,2-a] pyridines Process for the preparation of imidazo [1,2-a] pyridines

1977-06-16

1978-05-30

Ford, John M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424256, C07D47104

Patent

active

040923215

ABSTRACT:
Processes are described for the preparation of 2-(methoxycarbonylamino)-6-(phenylsulfinyl) imidazo [1,2-a] pyridine, which is an active anthelmintic agent. The process involves the treatment of a 5-phenylsulfinyl pyridine substituted at the 2-position with a leaving group, with methylchloroacetylcarbamate followed by treatment with ammonia.

REFERENCES:
patent: 3701780 (1972-10-01), Fisher
Fisher et al., Jr. of Medicinal Chem. vol. 15, pp. 982-985 (1972).
Krohrke et al., Chem. Ber., vol. 88, pp. 1117-1121, (1955).

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