Precursors for the production of chiral vicinal aminoalcohols

Details Precursors for the production of chiral vicinal aminoalcohols Precursors for the production of chiral vicinal aminoalcohols

1997-09-15

1999-08-24

Kumar, Shailendra

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

564148, 564149, 564150, 564151, 564170, 560312, C07C23305, C07C23908

Patent

active

059426446

ABSTRACT:
The disclosure describes new compositions of matter useful for the preparation of optically-active vicinal aminoalcohols. The compositions are chiral .beta.-hydroxycarboxamides, .beta.-hydroxyhydraxides, and .beta.-hydroxyhydroxamic acids.

REFERENCES:
Didier et al., "Chemo-enzymatic synthesis of 1,2- and 1,3-amino alcohols and their use in the enantioselective reduction of acetophenone and anti-acetophenone oxime methly ether with borane", Tetrahedron 47 (27): 4941-58 (1991).
Gotor, "Enzymic aminolysis, hydrzinolysis and oximolysis reactions", NATO ASI Ser., Ser. C 381 ; 199-208 (1992).
Pedrocchi-Fantoni et al., "Chiral amino alcohols from baker's yeast reduction of alpha keto acid derivatives", Gazz. Chim. Ital. 122 (12) : 499-502 (1992).
Geissman, T.A., Rearrangements Involving Electron-deficient Nitrogen in Principles of Organic Chemistry (W. H. Freeman & Co., 1962), pp. 674-675.
Stager et al, Tetrahedron, vol. 39, No. 10, pp. 1829-1836, 1983.
Fulop et al, J. Heterocyclic Chem., vol. 27, pp. 951-955, 1990.
Fulop et al, J. Chem. Soc, Perk. Trans., 1, pp. 2043-2048, 1984.
Quiros et al., Enantioselective reduction of .beta.-keto amides by the fungus Mortierella isabellina, 1997, pp. 3035-3038.
Ito, et al., "Highly Anti-Diastereoselective Reduction of 2-Alkyl-3-Oxo Amides By Potassium Triethylborohydride," Tetrahedron Letters, vol. 26, No. 38, pp. 4643-4646, 1985.
1997 Physician's Desk Reference pp. 1670-1673.
1992 C. Bull et al in "Biocatalytic Production of Amino Acids and Derivatives". pp. 255-256.
1992. Preparative Biotransformations, S.M. Roberts, Ed Chapter 2.
1996 A.U. Saksena et al, Tetrahedron Letters, 37 pp. 5657-5660.
1948 Tullar, B.F., J. Am. Chem. Soc, 70 2067-2078.
1986 D. Buisson and R. Azerad, Tetrahedron Letters, 27, 2631-2634.
1990 S. Servi, Synthesis, pp. 1-25.
1985 D. Seebach et al. Organic Synthesis, 63, 1-9.
1987 D.W. Brooks and K.W. Woods, J. Org. Chem., 53, 5215-5219.
1988 A. Faure and H. Veschambre, J. Org. Chem., 52, 5215-5219.
1978 M. Bucciarelli et al, J. Chem. Soc. Chem Comm., pp. 456-457.
1984 U. Ureslich in Biotransformations, vol. 6a, Chapter O.
1980 Z. Shaked and G.M. Whitesides, J. Am. Chem. Soc., 102, 7104-7105.
1984 J. B. Jones and T. Takemura, Canadian J. Chem, 62, 77-80.
1949 E.S. Wallis and J. F Lane Organic Reactions III, Chapter 7, pp. 207-306.
1969 P.A S. Smith, Trans. N.Y. Acad. Sci, 31, 504-515.
1973 S. Simons Jr., J. Org Chem. 38 414-416.
1976 W.L.F. Armarego et al, J. Chem Soc. Perkin Trans I., 2229-2237.
1974 S. Bittner et al, Tet. Lett. 23, 1965-1968.
1974 L. Bauer and O. Exner, Angew. Chem. Int. Ed., 13, 376-384.
1946 P.A.S. Smith, Organic Reactions. III, Chapter 9, pp. 337-338.
1948 J. H. Saunders and R. J. Slocombe, Chem. Rev. 43, 203-218.
1971 D. V. Banthorpe in "The Chemistry of the Azido Group ", Chapter 7, pp.397-405.
1980 J. D. Warren and J.B. Press, Synth. Comm., 10107-110.

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