Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1986-03-18
1988-11-08
Lee, Mary C.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
540597, 540610, 544128, 544131, 544165, 544169, 544172, 544363, 544365, 544399, 544400, 546155, 546156, 546159, 546169, 546170, 546193, 546194, 546208, 546210, 546211, 546232, 546233, 546234, 546261, 546278, 546279, 546281, 546292, 546318, 546322, 548300, 548341, 548342, 548353, 548378, 548561, 548566, 548567, 548578, 548579, 560 21, 560 22, 560 37, 560 61, 562435, 562437, 562442, 564166, 564184, C07D21380, C07D21382, C07D23112, C07D23306
Patent
active
047835354
ABSTRACT:
A process for the preparation of 1,4-oxazepinones and thiones having the formula: ##STR1## wherein A is an aromatic ring selected from benzene, naphthalene, quinoline or pyridine; n is 1 to 3; Z is an amino radical; R is hydrogen, loweralkyl, cycloalkyl or phenylloweralkyl; and R.sup.4 and R.sup.5 are hydrogen and loweralkyl starting from chloroaromatic carboxylates and alkanolamines is disclosed. The oxazepinones and oxazepinethiones prepared by the process have utility as antihistaminics with low sedative potential. Novel intermediate compounds are also disclosed.
REFERENCES:
patent: 4566899 (1986-01-01), Ambrosi et al.
Cale, Jr. Albert D.
Lo Young S.
A. H. Robins Company Incorporated
Briscoe Kurt G.
Lee Mary C.
LandOfFree
Chemical intermediates in the preparation of aromatic-1,4-oxazep does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Chemical intermediates in the preparation of aromatic-1,4-oxazep, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chemical intermediates in the preparation of aromatic-1,4-oxazep will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-464661