N-alkylnorscopines and acid addition salts thereof

Details N-alkylnorscopines and acid addition salts thereof N-alkylnorscopines and acid addition salts thereof

1987-03-31

1988-11-08

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D45106

Patent

active

047835346

ABSTRACT:
The invention relates to novel N-alkylnorscopines wherein the alkyl group may have 2 to 10 carbon atoms, which are useful in the preparation of valuable pharmaceutical compositions. These compounds may be prepared from the corresponding N-alkylnorscopolamines by hydrogenolysis with complex hydrides, which reaction is preferably carried out with sodium borohydride in ethanol at ambient temperature.

REFERENCES:
patent: 4608377 (1986-08-01), Banholzer et al.
Werner et al., Chem. Abstracts, vol. 67, (9), Abst. No. 43,974w, Aug. 28, 1967.
Banholzer et al., vol. 87, (17), Abst. No. 136,106t, Oct. 24, 1977.

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