Guanidine carboxylic acid esters and pharmaceutical preparations

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546278, 548336, 548342, 548196, 544331, 514397, 514400, 514371, 514275, A61K 31445, C07D40112

Patent

active

049488023

ABSTRACT:
New guanidine carboxylic acid esters corresponding to the general formula I ##STR1## and a process for the preparation of these compounds are described. The compounds according to the invention are H.sub.2 -agonists optionally having an additional H.sub.1 -antagonistic component. They are distinguished by their improved oral activity. The use of the above-mentioned guanidine carboxylic acid esters and of pharmaceutical preparations containing these esters is also described.

REFERENCES:
patent: 3881015 (1975-04-01), Black et al.
patent: 3968216 (1976-07-01), Black et al.
Chem. Abstracts 103:153321a, Durant et al.

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