Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1989-06-29
1990-08-14
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
A61K 31535
Patent
active
049487930
ABSTRACT:
The compounds and pharmaceutical compositions of Formula A, wherein Z is hydrogen or --C(O)R, Y is hydrogen or morpholinoethyl, and where R is lower alkyl or aryl, and the pharmaceutically acceptable salts thereof, are useful as immunosuppressive agents, particularly for treatment of allograft rejection, especially including cardiac allograft rejection, pancreatic allograft rejection and renal allograft rejection, and for treating autoimmune diabetes. ##STR1##
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"A Gastroprotective Anti-Inflammatory Agent: the .beta.-Morpholinoethyl Ester of Niflumic Acid (Morniflumate)", Schiantarelli et al., Agents and Actions, 14(2), 1984.
Allison Anthony C.
Eugui Elsie M.
Gu Chee-Liang L.
Lee William A.
Nelson Peter H.
Friedman Stanley J.
Lowin David A.
Moran Tom M.
Syntex (U.S.A.) Inc.
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