Stable allergenic extracts and methods

Details Stable allergenic extracts and methods Stable allergenic extracts and methods

1985-11-25

1987-12-29

Marantz, Sidney

Chemistry: analytical and immunological testing

Involving iga, igd, ige, or igm

210650, 424 88, 424 91, 424 98, 4241951, 436531, 436809, A61K 3900, G01N 3353

Patent

active

047161205

ABSTRACT:
A storage-stable, high potency allergenic extract is prepared by ultrafiltration, retaining fractions having molecular weights of from 1000 to 100,000, and treating the solution with gel polymer and/or carbon absorbents. The extract is dried to a moisture content of less than one weight percent water. The purified solution and aqueous reconstituted solutions of the dried extract provide a transparent, colorless solution which has greatly increased stability, remaining transparent and colorless for extended periods.

REFERENCES:
patent: 3983053 (1976-09-01), Courtney et al.
patent: 4350686 (1982-09-01), Relyveld et al.
patent: 4387091 (1983-06-01), Vijay et al.
Curtis, (1975), Allergenic Extracts Chapter 74, pp. 1344-1352, in: Remington's Pharmaceutical Sciences 15th Edition, Mack Publ. Co.

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