Phenylacetohydroxamic acids

Details Phenylacetohydroxamic acids Phenylacetohydroxamic acids

1978-02-13

1979-11-06

Evans, Joseph E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424315, C07C 8310, A61K 31185

Patent

active

041735773

ABSTRACT:
Phenylacetohydroxamic acids having the formula I ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4, independently of each other, represent hydrogen, chlorine, fluorine or bromine atoms or an alkyl or alkoxy group having at most 6 carbon atoms, and wherein R.sub.2 may additionally represent a trifluoromethyl group with the proviso that R.sub.1, R.sub.2 and R.sub.3 may not simultaneously represent hydrogen atoms and their pharmaceutically acceptable salts with bases, which compounds inhibit plateletaggregation and exhibit valuable pharmacological, in particular, antiphlogistic, analgesic and antipyretic activity.

REFERENCES:
patent: 3586713 (1971-06-01), Buu-Hoi et al.
patent: 3673243 (1972-06-01), Yamamoto et al.
patent: 3681445 (1972-08-01), Ruyle et al.
patent: 3692819 (1972-09-01), Carney
patent: 3697588 (1972-10-01), Vincent et al.
patent: 3821268 (1974-06-01), Diamond et al.
patent: 3828093 (1974-08-01), Bays et al.
patent: 3852323 (1974-12-01), Diamond et al.

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