Preparation of gamma-pyrones from 3-substituted furans

Details Preparation of gamma-pyrones from 3-substituted furans Preparation of gamma-pyrones from 3-substituted furans

1978-08-28

1979-11-06

Chan, Nicky

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D30922

Patent

active

041735722

ABSTRACT:
Gamma-pyrones are prepared by contacting a 3-halo-furfuryl alcohol or a 3-alkoxy-furfuryl alcohol with one equivalent of a halogen, peracid or peroxide oxidant and then heating until hydrolysis of the formed 4-substituted-dihydropyran intermediate is substantially complete. Maltol (2-methyl-3-hydroxy-4H-pyran-4-one) is prepared by this process from 2(1-hydroxyethyl)-3-alkoxy furans or 2(1-hydroxyethyl)-3-halo-furans. Gamma-pyrones are also prepared by contacting the corresponding 3-substituted-2,5-dialkoxy-furfuryl alcohols with acid until conversion to the gamma-pyrones is substantially complete.

REFERENCES:
Shono et al., Tetrahedron Letters, 17, 1363 (1976).
Laliberte et al., J. Med. Chem., 16, 1084 (1973).
Achmatowicz, Jr. et al., Tetrahedron, 32, 1051 (1976).
Achmatowicz, Jr. et al., Tetrahedron, 27, 1973 (1971).

Affiliated with

Also associated with

Rating

Preparation of gamma-pyrones from 3-substituted furans does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Preparation of gamma-pyrones from 3-substituted furans, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of gamma-pyrones from 3-substituted furans will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-461766