Control of life support systems

Surgery – Blood drawn and replaced or treated and returned to body

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A61M 3700

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active

059418419

ABSTRACT:
The flow of a biological fluid to an organ is computer-controlled so that the natural variation of such flow is simulated. Specifically described are control of a blood pump flow output during CPB to mimic normal pulsatile blood flow from the heart and control of a ventilator output to mimic normal breathing of healthy lungs. A pattern of variation over time of instantaneous flow of a biological fluid to an organ of a mammalian species is established, a variable control parameter for regulation of flow of the biological fluid to the organ is generated in accordance with the pattern, and the flow of biological fluid to the organ is controlled in accordance with the variable control parameter.

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Suki et al. (Nature, vol. 368, Apr. 1994, pp. 615-618).
Croughwell et al. (Ann. Thorac. Surg. 1994, 58:1702-1708).
Maeda, K. et al., Asaio Transactions, "Predictive Control by Physical Activity Rate of a Total Artificial Heart During Exercis", vol. 34, No. 3, Jul. 1988, 480-484.
Michael Heymann et al., "Blood Flow Measurements with Radionuclide-labeled Particles", Progress in Cardiovascular Diseases, vol. XX, No. 1 (Jul./Aug.), 1977, pp. 55-79.

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