Muco-bioadhesive composition

Details Muco-bioadhesive composition Muco-bioadhesive composition

1988-12-08

1990-08-14

Schofer, Joseph L.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424434, 424435, 424443, 424447, 424448, 424484, 514944, 514969, A61K 3174, A61K 906, A61K 600, A61F 1302

Patent

active

049485806

ABSTRACT:
A bioadhesive composition is provided which may be employed as an oral drug delivery system and includes a freeze-dried polymer mixture formed of the copolymer poly(methyl vinyl ether/maleic anhydride) and gelatin, which is dispersed in an ointment base such as mineral oil containing dispersed polyethylene. Such bioadhesive compositions may be used to deliver oral mucosa active ingredients such as steroids, anti-fungal agents, anti-bacterial agents and the like.

REFERENCES:
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patent: 3029188 (1962-04-01), Cyr et al.
patent: 3312594 (1967-04-01), Cyr et al.
patent: 3984571 (1976-10-01), Chen
patent: 4292972 (1981-10-01), Pawelchak et al.
patent: 4393080 (1983-07-01), Pawelchak et al.
patent: 4540602 (1985-09-01), Motoyama et al.
patent: 4542020 (1985-09-01), Jackson et al.
patent: 4569955 (1986-02-01), Dhabhar
Tsunenori et al., CA 104(10): 7507c.

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