Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-03-27
1990-11-20
Berch, Mark L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548429, C07D48704, A61K 3140
Patent
active
049719920
ABSTRACT:
This invention relates to 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-ol carbonate esters of the ##STR1## the pharmaceutically acceptable acid addition salts thereof and where applicable to the geometric and optical isomers and racemic mixtures thereof. The compounds of this invention display utility as analgesic agents.
REFERENCES:
patent: 4791107 (1988-12-01), Hamer
Harris et al., J. Pharm. Exp. Ther. 169, 17 (1969).
Furst, Eur. J. Pharmacol. 83, 233 (1982).
Pearl, J. Pharmacol. Exp. Ther. 160, 217 (1968).
Dewey, J. Pharm. Pharmacol. 21, 548 (1969).
Chiang Yulin
Glamkowski Edward J.
Kurys Barbara E.
Berch Mark L.
Hoechst-Roussel Pharmaceuticals Inc.
Rosenstock Jerome
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