Method of coating solid particles with a hydrophilic gel

Coating processes – Particles – flakes – or granules coated or encapsulated – Solid encapsulation process utilizing an emulsion or...

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4272133, 210635, 210656, 502403, 502439, 435177, B01J 1304, B01D 1508, G01N 3048

Patent

active

049718339

ABSTRACT:
Methods for coating hydrophilic gels onto the surface of solid particles are disclosed which include utilizing hydrophilic solid particles, intimately admixing these hydrophilic solid particles with a hydrophilic gel-forming substance at a temperature above the gelling temperature so as to coat the solid hydrophilic particles, and then separating these coated particles from each other and cooling them to a temperature below the gelling temperature. The use of these coated particles is also disclosed in connection with various separation processes, such as an ion exchanger, in those cases where the gel-forming substance contains charged groups, or providing the particles with suitable adsorbent groups.

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"Agarose Gels in HPLC Separation of Biopolymers," S. Hjerten, Trends in Analytical Chemistry, vol. 3, No. 3, Mar. 1984, pp. 87-90.

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