Treatment of tardive dyskinesia in mammals

Details Treatment of tardive dyskinesia in mammals Treatment of tardive dyskinesia in mammals

1982-07-06

1984-01-10

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

A61K 31135

Patent

active

044253630

ABSTRACT:
A method of Treatment of Tardive Dyskinesia (TD) in humans by the administration of the compound of the formula ##STR1## or a pharmaceutically acceptable acid addition salt thereof in a non-toxic, effective therapeutic amount (calculated as base) to a human in need thereof.

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Laakmann et al., Life Sciences, vol. 30, pp. 1725-1732, (1982), Pergamon Press.
Butz et al., Inpress: Jour. Exp. Pharmacology of Therapeutics, (1982), The Relationship Between Bupropion Disposition & Dopamine Uptake in Rats and Mice.
Ferris et al., Typical & Atypical Antidepressants, Molecular Mechanisms, Raven Press, New York, (1982), pp. 277-286.
Ferris et al., Drug Development Research 1: 21-35, (1981).
Soroko et al., Communications, J. Pharm. Pharmac., (1977), 29, 767-770.
Canning et al., Brit. Jour. of Pharmacology, (1979): 66 104-105.
Whiteman et al., Jour. of Clin. Psychiatry, (1982), Failure of Bupropion to Affect Prolacter or Growth Hormone.
Pharmacological and Biochemical Properties of Drug Substances, vol. 3, "Bupropion", Maxwell et al., Amer. Pharm. Ass. Academy of Pharm. Sciences Publish.

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