Thienylpiperazinones, their preparation and their use

Details Thienylpiperazinones, their preparation and their use Thienylpiperazinones, their preparation and their use

1989-05-09

1990-02-06

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544379, A61K 31495, C07D40304

Patent

active

048988669

ABSTRACT:
3-(Thien-2-yl)-piperazin-2-ones, substituted in the 3-position, of the general formula ##STR1## wherein R dentoes, for example, phenyl or (C.sub.1 -C.sub.6)-alkyl and R.sup.1 denotes 2-thienyl and pharmacologically tolerable acid addition salts thereof, which possess valuable nootropic properties. The invention also includes methods for making such compounds, formulations containing such compounds and methods for treating a host in need thereof.

REFERENCES:
patent: 3056784 (1962-10-01), Carr, Jr. et al.
patent: 3390139 (1968-06-01), de Benneville
patent: 4598079 (1986-07-01), Beyerle et al.

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