Dihydropyridine-sensitive calcium channel as a tumor associated

Details Dihydropyridine-sensitive calcium channel as a tumor associated Dihydropyridine-sensitive calcium channel as a tumor associated

1987-08-06

1990-09-04

Warden, Robert J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

424 11, 424 9, 435 28, 4351722, 43524077, 436501, 436503, 436512, 436548, 436813, 530350, 530387, 935106, 935107, 935110, G01N 3353, G01N 33566, A61K 3900, C07K 1514

Patent

active

049544365

ABSTRACT:
A protein antigen related to the dihydro-pyridine-sensitive calcium channel is expressed at high levels by small cell carcinoma of the lung and neuroblastomas. The antigen serves as a marker which can be exploited for diagnosis and therapy of these tumors. Methods of diagnosis and therapy of small cell carcinoma of the lung and neuroblastomas employing monoclonal antibodies which are specific for the dihydropyridine-sensitive calcium channel are also described.

REFERENCES:
patent: 4690935 (1987-09-01), Taylor et al.
patent: 4784955 (1988-11-01), Campbell
patent: 4784958 (1988-11-01), Glossman
Flockeral et al., Nature, vol. 323, Sep. 1986, pp. 66-68.
Curtis et al., Biochemistry, vol. 23, No. 10, May 1984, pp. 2113-2118.
Leung A. T. et al., J. Biol. Chem. 262(17), 1987.
Chin, H. et al., Soc. Neurosci. Abst. 13:99, 1987.
Smilowitz, J. et al.; Soc. Neurosci. Abst. 13:99, 1987.
Norman et al., FEBS Letters, vol. 212, No. 1, Feb. 1987, pp. 127-132.
Cooper et al., The Journal of Biological Chemistry, vol. 262, No. 2, Jan. 1987, pp. 509-512.
Takahashi et al., Science, vol. 236, No. 4797, Apr. 1987; pp. 88-91.

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