Process for preparing thiophene derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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549 61, C07D33336, C07D33338

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048473863

ABSTRACT:
A process for the preparation of 3-aminothiophenes or acid-addition salts thereof, which comprises reacting the corresponding 3-oxotetrahydrothiophenes with an acid-addition salt of hydroxylamine in the presence of a polar inert solvent and in the absence of a base at a temperature in the range of from 0.degree. to 200.degree. C.

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patent: 4317915 (1982-03-01), Confalone et al.
patent: 4428963 (1984-01-01), Confalone et al.
Baker, B. R., et al., J. Org. Chem., 18, 138-152, (1953).

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