Resolution of enantiomers of 2-(4-aryloxyphenoxy) propionic acid

Details Resolution of enantiomers of 2-(4-aryloxyphenoxy) propionic acid Resolution of enantiomers of 2-(4-aryloxyphenoxy) propionic acid

1987-08-05

1988-11-22

Lone, Werren B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

546295, 71 92, 71 94, 71109, 71116, 560 62, 562401, 562472, C07D24136, C07D21172, C07B 5700

Patent

active

047867329

ABSTRACT:
A method for the effective chromatographic resolution and analysis of the enantiomers of 2-(4-aryloxyphenoxy)propionic acids which comprises dissolving a 2-(4-aryloxyphenoxy)propionic acid in a suitable solvent, injecting the solution into a liquid chromatographic system and eluting the components from the column using an eluent contain R-(-)- or S-(+)-2-pyrrolidinemethanol and an alkanoic acid in a suitable solvent.

REFERENCES:
patent: 3954442 (1976-05-01), Becker et al.
patent: 4332960 (1982-01-01), Trosken et al.
patent: 4370489 (1983-01-01), Boesenberg et al.
patent: 4531969 (1985-07-01), Nestler et al.
patent: 4550192 (1985-10-01), Rogers et al.
patent: 4565568 (1986-01-01), Johnston et al.
patent: 4609396 (1986-09-01), Fawzi
Wainer, Liquid Chromatography in Pharmaceutical Development: An Introduction, Aster Publ. Corp. Springfield, Ore., pp. 110-125, (1985).
Wainer, Chromatography Forum, 1, (4), 55-61, (1986).
Souter, CRC Press, Boca Raton, Florida, pp. 103, 155, 157, 174, 187, and 189; (1985).
Petterson et al., Journal of Liquid Chromatography, 9(2&3), pp. 269-290, (1986).

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