Compositions and methods of use of ORF-1358 from...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

Reexamination Certificate

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C424S185100, C424S190100, C435S975000, C530S350000

Reexamination Certificate

active

08071112

ABSTRACT:
The present invention relates to polynucleotides encodingStreptococcusgroup C and G polypeptides and their use in immunogenic compositions. The invention also relates to immunogenic compositions comprising polypeptides encoded by those polynucleotides. In addition, the invention relates to methods of inducing an immune response in mammals against beta hemolyticStreptococcusor beta hemolyticStreptococcusinfection using immunogenic compositions of theStreptococcusgroup C and G polypeptides and polynucleotides.

REFERENCES:
patent: WO02/34771 (2002-05-01), None
patent: WO02/083859 (2002-10-01), None
patent: WO2005/076010 (2005-08-01), None
patent: WO2006/042027 (2006-04-01), None
Banks DJ et al; J. Infect. Dis. 190:727-738 (2004).
Beres SB et al; Proc. Natl. Acad. Sci U.S.A. 103(18):7059-7064 (2006).
Efstratiou A; J of Medical Microbiology 29(3):207-220 (1989).
NCBI Genbank, zinc-binding adhesion liprotein [Streptococcus agalactiae2603V/R], NP—687564.1 GI:22536713, accessed Aug. 19, 2010.
NCBI Genbank, High-affinity zinc uptake system protein znuA precursor[Streptococcus pyogenesMGAS10394], AAT86698.1, GI:50902983, accessed Aug. 19, 2010.
PCT International Search Report—Jan. 21, 2010.
Smoot JC et al; Proc. Natl. Acad. Sci. U.S.A. 99(7):4668-4673 (2002).
Sumby P. et al; J. Infect. Dis. 192:771-782 (2005).

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