Certain substituted amides, method of making, and method of...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S333000

Reexamination Certificate

active

08058446

ABSTRACT:
At least one chemical entity chosen from compounds of Formula 1and pharmaceutically acceptable salts, solvates, chelates, non-covalent complexes, prodrugs, and mixtures thereof is described herein.Pharmaceutical compositions comprising at least one chemical entity of the invention, together with at least one pharmaceutically acceptable vehicle chosen from carriers adjuvants, and excipients, are described.Methods of treating patients suffering from certain diseases responsive to inhibition of Btk activity and/or B-cell activity are described. Methods for determining the presence of Btk in a sample are described.

REFERENCES:
patent: 6221900 (2001-04-01), Uckun et al.
patent: 2008/0153834 (2008-06-01), Blomgren et al.
patent: 2009/0082330 (2009-03-01), Blomgren et al.
patent: 2010/0160292 (2010-06-01), Whitney et al.
patent: WO 2006/065946 (2006-06-01), None
patent: WO 2006/099075 (2006-09-01), None
patent: WO 2007/027729 (2007-03-01), None
patent: WO 00/43373 (2007-07-01), None

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