Cardiac arrhythmias analysis of electrophysiological signals...

Surgery – Diagnostic testing – Cardiovascular

Reexamination Certificate

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C600S518000, C600S523000

Reexamination Certificate

active

08086303

ABSTRACT:
The disclosed method analyzes cardiac electrophysiological signals, including ECG and internal cardiac electrograms, based on multi-level symbolic complexity calculation and multi-dimensional mapping. The results may be used to objectively identify cardiac disorders, differentiate cardiac arrhythmias, characterize pathological severities, and predict life-threatening events. Multi-level symbolization and calculation of the electrophysiological signal is used provide better reliability and analysis resolution for identifying and characterizing cardiac disorders. Adaptive analysis of the cardiac signal complexity enables calculation efficiency and reliability with high SNR, and with low calculation volume and power consumption. One dimension (time or frequency domain) and multi-dimension symbolic analysis is used to provide more information of cardiac pathology and high risk rhythm transition to doctors.

REFERENCES:
patent: 6490478 (2002-12-01), Zhang
patent: 2007/0066906 (2007-03-01), Goldberger et al.
patent: 2007/0129639 (2007-06-01), Zhang
Zhang et al., “Detecting ventricular tachycardia and fibrillation by complexity measure”, IEEE Trans Biomed Eng, 46: 548-55, 1999.
Zhang et al., “Qualitative chaos analysis for ventricular tachycardia and fibrillation based on symbolic complexity”, Medical Engineering & Physics, ISSN 1350-4533, vol. 23, No. 8, pp. 523-528, 2001.
Takens, “Detecting strange attractors in turbulence”, in: Rand, D.A. and Young, L.S. (Eds) (Springer, Berlin, Heidelberg, New York), pp. 366-387, 1981.
Lempel et al., “On the complexity of finite sequences”, IEEE Trans. On IT 22, pp. 75-81, 1976.
Zhang et al., “Complexity measure and complexity rate information based detection of ventricular tachycardia and fibrillation”, Medical and Biomedical Engineering and Computing, vol. 38, No. 5, pp. 553-557, 2000.

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