Pyridine, quinoline, and isoquinoline N-oxides as kinase...

Details Pyridine, quinoline, and isoquinoline N-oxides as kinase... Pyridine, quinoline, and isoquinoline N-oxides as kinase...

2010-01-25

2011-12-06

Davis, Zinna Northington (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S314000, C514S332000, C514S345000, C514S352000, C514S354000, C546S143000, C546S159000, C546S255000, C546S290000, C546S304000

Reexamination Certificate

active

08071616

ABSTRACT:
This invention relates to urea compounds containing a pyridine, quinoline, or isoquinoline functionality which is oxidized at the nitrogen heteroatom and which are useful in the treatment of (i) raf mediated diseases, for example, cancer, (ii) p38 mediated diseases such as inflammation and osteoporosis, and (iii) VEGF mediated diseases such as angiogenesis disorders.

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