Dialkylamino alkyl esters of pivagabine as medicaments for...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S563000

Reexamination Certificate

active

08080548

ABSTRACT:
The present embodiments are related to the compound of Formula 1 or Formula 2 below and pharmaceutical formulations thereof as well as treatments for a wide variety of Central Nervous System disorders with the pharmaceutical formulations. Some embodiments include the use of a variety of the instant compounds which surprisingly and advantageously exhibit improved pharmacokinetic and therapeutic profiles in comparison to pivagabine.

REFERENCES:
patent: 2003/0176398 (2003-09-01), Gallop et al.
patent: 2005/0009814 (2005-01-01), Iwayama et al.
patent: WO98/38988 (1998-09-01), None
Gary Stix, Science American, p. 51-57 (Jun. 2010).
Gerra et al., Behavioural Brain Research, V122 (2001), p. 93-101.
Boussard et al., Bioploymers, 1977, 16(5), pp. 1033-1052, Abstract.

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