Clostridial toxin activity assays

Details Clostridial toxin activity assays Clostridial toxin activity assays

2006-04-04

2011-11-29

Kam, Chih-Min (Department: 1656)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

C435S029000, C424S236100, C424S239100, C530S350000, C536S023700

Reexamination Certificate

active

08067231

ABSTRACT:
Compositions useful for detecting Clostridial toxin activity comprising a cell that contains an exogenous Clostridial toxin substrate which comprises a fluorescent member, a membrane targeting domain and a Clostridial toxin recognition sequence comprising a cleavage site, where the cleavage site intervenes between the fluorescent member and the membrane targeting domain; and methods useful for determining Clostridial toxin activity using such Clostridial toxin substrates.

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