Isoquinolines as IGF-1R inhibitors

Details Isoquinolines as IGF-1R inhibitors Isoquinolines as IGF-1R inhibitors

2006-09-08

2011-10-25

Davis, Zinna Northington (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S309000, C546S139000, C546S141000, C546S144000

Reexamination Certificate

active

08044067

ABSTRACT:
Compounds of the formula (I):were synthesized. In at least one embodiment, they were found to down-regulate or inhibit the expression or function of the IGF-1 receptor.

REFERENCES:
patent: 7875631 (2011-01-01), Gunzinger et al.
patent: WO 01/32624 (2001-05-01), None
patent: WO 2004/054996 (2004-07-01), None

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