Use of acetals for isolation of nucleic acids

Details Use of acetals for isolation of nucleic acids Use of acetals for isolation of nucleic acids

2009-06-09

2011-11-22

Whisenant, Ethan C (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C536S025400

Reexamination Certificate

active

08062843

ABSTRACT:
The invention provides the use of water-miscible liquid cyclic acetals for adsorbing a nucleic acid to a solid phase such as a substrate with a silica surface. To this end, the invention also provides compositions comprising said acetals. Methods are disclosed and claimed to purify nucleic acids from samples, as well as kits useful for performing these methods. The nucleic acids purified by a method of the invention are suited for assays aiming at the detection of a target nucleic acid.

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