Chiral indole intermediates and their fluorescent cyanine...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C435S004000, C435S006120, C435S007100, C435S007200, C546S028000

Reexamination Certificate

active

08044203

ABSTRACT:
This invention relates to the functionalized cyanine dyes and more particularly, to the synthesis of chiral 3-substituted 2,3′-dimethyl-3H-indole and its derivatives as intermediates for preparation of cyanine dyes, to methods of preparing these dyes and the dyes so prepared.

REFERENCES:
patent: 5268486 (1993-12-01), Waggoner et al.
patent: 6133445 (2000-10-01), Waggoner et al.
patent: 6180087 (2001-01-01), Achilefu et al.
patent: 7408062 (2008-08-01), Waggoner et al.
patent: 2 425 705 (2002-04-01), None
patent: WO 00/75237 (2000-12-01), None
patent: WO 02/26891 (2002-04-01), None
patent: WO 02/26891 (2002-04-01), None
patent: WO 02/32466 (2002-04-01), None
Handbook of Fluorescent Probes and Research Products, Richard P. Haughland, 9thEdition, Molecular Probes (2002).
Non-Radioactive Labelling: A Practical Introduction, Biological Techniques Series, Andrew J. Garman, Academic Press (1997).
Bioconjugation—Protein Coupling Techniques for the Biomedical Sciences, Mohammed Aslam and Alastair Dent. Macmillan (1998).
Brinkley, “A Brief Survey of Methods for Preparing Protein Conjugates with Dyes, Haptens, and Cross-Linking Reagents”, Bioconjugate Chemistry (1992), vol. 3, No. 1, pp. 2-13.
Supplementary European Search Report dated Apr. 28, 2005, issued in connection with EP 03 80 8367.
Capper et al, “Assessing a Training Screen Employing Image-based Cellular Assays—Antagonist GPCR assays in live-cells with CypHer5E”, Poster presented at the 10thSBS Conference, Orlando, Florida, Sep. 10-15, 2004.
Newman et al, “Detection of Agonist-mediated Internalization of Endogenous EGF Receptors Using CypHer5E”, 4thBPS Focused Meeting on Cell Signaling, Leicester, UK Apr. 11-12, 2005.
Beletskii et al, “High-throughput phagocytosis assay utilizing a pH-sensitive fluorescent dye”, BioTechniques 39(6):894-897, Dec. 2005.
Screening for potential β2-adrenergic receptor antagonists using CypHer5E and IN Cell Analyzer 1000, in Discovery Matters Issue 3, p. 13, Mar. 2006.
Optimization of CypHer5E labeled anti-VSV-G antibody for use in receptor internalization assays, Discovery Matters Issue 5, p. 17, Mar. 2007.

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