Spirocyclic azaadamantane derivatives and methods of use

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C546S018000

Reexamination Certificate

active

08076350

ABSTRACT:
The invention relates to compounds that are spirocyclic azaadamantane derivatives derivatives, particularly spirocyclic azaadamantanyl ether or amine derivatives, compositions comprising such compounds, methods of using such compounds and compositions, processes for preparing such compounds, and intermediates obtained during such processes.

REFERENCES:
patent: 2002/0045617 (2002-04-01), Grewal et al.
patent: 1359152 (2003-05-01), None
patent: 0181347 (2001-11-01), None
patent: 2004064836 (2004-08-01), None
patent: 2005028477 (2005-03-01), None
patent: 2006005233 (2006-06-01), None
patent: 2007038058 (2007-04-01), None
Adams, C., et al., Developmental Brain Research, 139: 175-187 (2002).
Adler, L. E., et al., Schizophrenia Bulletin, 24: 189-202 (1998).
Becker, D.P., et al, Synthesis, 1080-1082 (1992).
Bitner R., et al., Soc. Neuroscience, Abstract 325.6 (2006).
Buck, E., et al., Org. Lett., 4: 1623-1626 (2002).
Charles, M., et al, Org. Lett., 7(18): 3965-3968 (2005).
Cordero-Erausquin, M., et al., PNAS, 98: 2803-2807 (2001).
Eliel, E., et al., “Stereochemistry of Organic Compounds”, John Wiley & Sons, Inc., New York, NY, Table of Contents (1994).
Falk, L., et al., Developmental Brain Research, 142: 151-160 (2003).
Friedman, J., et al., Biol. Psychiatry, 51: 349-357 (2002).
Furniss, et al., Vogel's Textbook of Practical Organic Chemistry, 5th edition, Longman Scientific & Technical, Essex CM20 SJE, England, Table of Contents (1989).
Greene, T., et al., Protective Groups in Organic Synthesis, 3rd edition, John Wiley & Sons, New York, Table of Contents (1999).
Higuchi, T., et al., Prodrugs as Novel Delivery Systems, vol. 14 of the A.C.S. Symposium Series, Washingon D.C., Table of Contents (1975).
Roche, E., Bioreversible Carriers in Drug Design, American Pharmaceutical Association and Pergamon Press, New York, NY, Table of Contents (1987).
Heeschen, C., et al., The Journal of Clinical Investigation, 110(4): 527-536 (2002).
Heeschen, C., et al., Nature Medicine, 7(7): 833-839 (2001).
IUPAC 1974 Recommendations for Section E, Fundamental stereochemistry, Pure Appl. Chem., 45: 13-30 ( 1974).
Jacobi, J., et al., American Journal of Pathology, 161(1): 97-104 (2002).
Jonnala, R., et al., J. Neurosci. Res., 66: 565-572 (2001).
Kesel, A., Current Medicinal Chemistry, 12(18): 2095-2162 (2005).
Kihara, T., et al., J. Biol. Chem., 276: 13541-13546 (2001).
Leonard, S., et al., Eur. J. Pharmacol., 393: 237-242 (2000).
Levin, E., J. Neurobiol., 53: 633-640 (2002).
Liu, Q., et al., PNAS, 98: 4734-4739 (2001).
Pabreza, L., et al., Molecular Pharmacology, 39: 9-12 (1990).
Paterson, D., et al., Progress in Neurobiology, 61: 75-111 (2000).
Prescott, Ed., Methods in Cell Biology, Academic Press, New York, NY, p. 33 et seq. (1976).
Radek R., et al., Psychopharmacology, 187: 47-55( 2006).
Rowley, M., et al., Journal of Med. Chem., 44(4): 477-501 (2001).
Sawa, A., et al., Mol. Med., 9: 3-9 (2003).
Shimohama, S., et al., Brain Res., 779: 359-363 (1998).
Son, J., et al., Biology of Reproduction, 68: 1348-1353 (2003).
Stetter, H., et al., Chemische Berichte, 105: 2773-2779 (1972).
Stevens, K., et al., Psychopharmacology, 136: 320-327 (1998).
Tsuneki, H., et al., J. Physiol., 547: 169-179 (2003).
Wang, H., et al., 421: 3984-388 (2003).
PCT International Search Report, PCT Application No. PCT/US2007/085566, mailing date Mar. 20, 2008.
Wilens, T., et al., American Journal of Psychiatry 156(12): 1931-1937 (1999).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Spirocyclic azaadamantane derivatives and methods of use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Spirocyclic azaadamantane derivatives and methods of use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Spirocyclic azaadamantane derivatives and methods of use will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4293782

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.