Phthalazine derivatives with angiogenesis inhibiting activity

Details Phthalazine derivatives with angiogenesis inhibiting activity Phthalazine derivatives with angiogenesis inhibiting activity

2010-11-24

2011-10-11

Habte, Kahsay T (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S116000, C544S238000

Reexamination Certificate

active

08034814

ABSTRACT:
The invention relates to new phthalazine derivatives of formula I,and to processes for the preparation thereof, the application thereof in a process for the treatment of the human or animal body, the use thereof alone or in combination with one or more other pharmaceutically active compounds for the treatment especially of a disease that responds to the inhibition of especially the vascular endothelial growth factor receptor kinase, preferably the treatment of a proliferative disease, or the treatment of inflammatory rheumatic or rheumatoid arthritis and/or pain; and the use of such a compound alone or in combination with one or more other pharmaceutically active compounds for the manufacture of a pharmaceutical preparation for the treatment of said diseases in an animal.

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