Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2008-11-26
2011-10-04
Kifle, Bruck (Department: 1622)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S254020, C514S260100, C514S312000, C514S378000, C514S381000, C514S411000, C514S413000, C540S455000, C540S461000
Reexamination Certificate
active
08030307
ABSTRACT:
The present invention relates to compounds of Formula I or pharmaceutically acceptable salts, esters, or prodrugs thereof:which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising a compound of the present invention.
REFERENCES:
patent: 6037157 (2000-03-01), Norbeck et al.
patent: 6323180 (2001-11-01), Llinas-Brunet et al.
patent: 6608027 (2003-08-01), Tsantrizos et al.
patent: 6995174 (2006-02-01), Wang et al.
patent: 7037911 (2006-05-01), Zhang
patent: 7125845 (2006-10-01), Wu et al.
patent: 7132504 (2006-11-01), Scola et al.
patent: 7135462 (2006-11-01), Scola et al.
patent: 7173004 (2007-02-01), McPhee et al.
patent: 7176208 (2007-02-01), Nakajima et al.
patent: 7273851 (2007-09-01), Miao et al.
patent: 2005/0153877 (2005-07-01), Miao et al.
patent: 2005/0261200 (2005-11-01), Miao et al.
patent: 2005/0267018 (2005-12-01), Blatt et al.
patent: 2006/0122123 (2006-06-01), Chaudhary et al.
patent: 2007/0099825 (2007-05-01), D'Andrea et al.
patent: 2007/0281884 (2007-12-01), Sun et al.
patent: 2007/0281885 (2007-12-01), Sun et al.
patent: 2008/0032936 (2008-02-01), Gai et al.
patent: 2008/0039375 (2008-02-01), Moore et al.
patent: 2008/0125444 (2008-05-01), Sun et al.
patent: 2008/0181868 (2008-07-01), Sun et al.
patent: 2008/0187516 (2008-08-01), Sun et al.
patent: 2008/0274082 (2008-11-01), Gai et al.
patent: 2009/0005387 (2009-01-01), Niu et al.
patent: 2009/0035271 (2009-02-01), Sun et al.
patent: 2009/0098085 (2009-04-01), Sun et al.
patent: 2009/0142299 (2009-06-01), Sun et al.
patent: 2009/0175822 (2009-07-01), Moore et al.
patent: 2009/0180981 (2009-07-01), Niu et al.
patent: 2009/0180984 (2009-07-01), Sun et al.
patent: 2009/0191153 (2009-07-01), Sun et al.
patent: 2009/0197888 (2009-08-01), Gai et al.
patent: 2009/0202485 (2009-08-01), Gai et al.
patent: 2009/0202486 (2009-08-01), Gai et al.
patent: 2009/0238794 (2009-09-01), Gai et al.
patent: 2010/0003214 (2010-01-01), Gai et al.
patent: 2004072243 (2004-08-01), None
patent: 2004093915 (2004-11-01), None
patent: 2005010029 (2005-02-01), None
patent: 2008021960 (2008-02-01), None
J. R. Herr, “A Whirlwind Tour of Current Mitsunobu Chemistry”, Albany Molecular Research Inc., Technical Report, 1999, vol. 3, No. 19, pp. 1-36 (especially pp. 11-12).
International Search Report PCT/US08/84886, Jan. 22, 2009.
Moore Joel D.
Or Yat Sun
Wang Zhe
Elmore Carolyn S.
Elmore Patent Law Group P.C.
Enanta Pharmaceuticals, Inc.
Harlan Edgar W.
Kifle Bruck
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