Covalent conjugates between artemisinin-related...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C514S001100, C514S005400, C514S018900, C514S019200, C514S019300, C549S349000, C530S300000, C424S001690

Reexamination Certificate

active

08048850

ABSTRACT:
In one aspect, the invention provides covalent conjugates between artemisinin-related endoperoxides and iron-carrying proteins. In some embodiments, the covalent conjugates comprise artelinate and holotransferrin. In another aspect, the invention provides methods for administering the covalent conjugates of the invention to treat cancer and infections by pathogens that bind iron-carrying proteins.

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