Optimized anti-CD20 monoclonal antibodies having Fc variants

Details Optimized anti-CD20 monoclonal antibodies having Fc variants Optimized anti-CD20 monoclonal antibodies having Fc variants

2005-06-30

2011-12-27

Dahle, Chun (Department: 1644)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

C530S387300, C530S388100, C530S388220

Reexamination Certificate

active

08084582

ABSTRACT:
The present invention relates to optimized CD20 antibodies having Fc variants, methods for their generation, and method for their application, such as methods of enhancing macrophage activation, particularly for therapeutic purposes.

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