Method for producing ultrafine submicronic suspensions

Details Method for producing ultrafine submicronic suspensions Method for producing ultrafine submicronic suspensions

2006-03-09

2011-10-11

Wax, Robert A (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

Reexamination Certificate

active

08034381

ABSTRACT:
The invention concerns a method for producing ultrafine suspensions, characterized in that a substance in the form of a solid product at 20° C. is dissolved in a solvent, in that the solvent is very rapidly substantially drawn from said solution, in that the powder thus obtained, whereof the particles have an average particle-size distribution of the order of 1 to 50 μm (by laser diffractometry) is dispersed in a dispersing medium, and in that the resulting suspension is treated subsequently, using average to high forces, so as to obtain a suspension whereof the solid matter particles have a average particle-size distribution (by photon correlation spectroscopy) less than 3 μm, preferably less than 1 μm (1000 nm), and in particular less than 400 nm, more particularly still, less than 200 nm.

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