Salts of bazedoxifene

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C540S602000

Reexamination Certificate

active

08034807

ABSTRACT:
The invention deals with new crystalline salts of bazedoxifene, by means of which a high API quality can be achieved in a high yield.

REFERENCES:
patent: 5998402 (1999-12-01), Miller et al.
patent: 6479535 (2002-11-01), Pickar et al.
patent: 2005/0227964 (2005-10-01), Fawzi et al.
patent: 2005/0227965 (2005-10-01), Demerson et al.
patent: 2005/0227966 (2005-10-01), Shah et al.
patent: WO 2006/104791 (2006-10-01), None
International Search Report of international Patent Application No. PCT/CZ2002/000089, Date of Mailing: Jun. 17, 2009.
Chris P. Miller, Bazedoxifene Acetate, Selective Estrogen Receptor Modulator Treatment and Prevention of Osteoporosis, Drugs of the Future 2002, 117-121, 27(2).
Chris P. Miller, Design, Synthesis, and Preclinical Characterization of Novel, Highly Selective Indole Estrogens, Journal of Medical Chemistry, 2001, 1654-1657, 44.

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