Fluorescent nanoparticle scope

Details Fluorescent nanoparticle scope Fluorescent nanoparticle scope

2007-06-29

2011-11-22

Leubecker, John P (Department: 3779)

Surgery

Endoscope

Having imaging and illumination means

C600S181000, C600S112000

Reexamination Certificate

active

08062215

ABSTRACT:
Various compositions, methods, and devices are provided that use fluorescent nanoparticles to function as markers, indicators, and light sources. In one embodiment, an endoscopic adaptor is provided for viewing fluorescent nanoparticles. The adaptor can be configured to removably mate to a portion of an endoscope, such as an eyepiece, and it can be adapted to contain a filter for filtering light received through the viewing lumen of the eyepiece. In an exemplary embodiment, the filter is configured to transmit fluorescent light while blocking visible light, to thereby enable a structure containing one or more fluorescent nanoparticles to be viewed through the endoscope.

REFERENCES:
patent: 4212304 (1980-07-01), Finney
patent: 4264167 (1981-04-01), Plummer
patent: 4554088 (1985-11-01), Whitehead et al.
patent: 4628037 (1986-12-01), Chagnon et al.
patent: 4655569 (1987-04-01), Sims
patent: 4672040 (1987-06-01), Josephson
patent: 4807026 (1989-02-01), Nishioka et al.
patent: 4862199 (1989-08-01), Centkowski et al.
patent: 5176625 (1993-01-01), Brisson
patent: 5295954 (1994-03-01), Sachse
patent: 5406418 (1995-04-01), Deary
patent: 5408996 (1995-04-01), Salb
patent: 5531741 (1996-07-01), Barbacci
patent: 5678555 (1997-10-01), O'Connell
patent: 5701903 (1997-12-01), Sano et al.
patent: 5749830 (1998-05-01), Kaneko et al.
patent: 5772580 (1998-06-01), Utsui et al.
patent: 5861027 (1999-01-01), Trapp
patent: 5879306 (1999-03-01), Fontenot et al.
patent: 5954652 (1999-09-01), Heyman
patent: 6013531 (2000-01-01), Wang et al.
patent: 6025873 (2000-02-01), Nishioka et al.
patent: 6028622 (2000-02-01), Suzuki
patent: 6030339 (2000-02-01), Tatsuno et al.
patent: 6044845 (2000-04-01), Lewis
patent: 6069651 (2000-05-01), Tsuyuki et al.
patent: 6110106 (2000-08-01), MacKinnon et al.
patent: 6293911 (2001-09-01), Imaizumi et al.
patent: 6310354 (2001-10-01), Hanninen et al.
patent: 6344272 (2002-02-01), Oldenburg et al.
patent: 6364855 (2002-04-01), Zappala
patent: 6395021 (2002-05-01), Hart et al.
patent: 6484049 (2002-11-01), Seeley et al.
patent: 6510338 (2003-01-01), Irion et al.
patent: 6530944 (2003-03-01), West et al.
patent: 6636755 (2003-10-01), Toida
patent: 6773812 (2004-08-01), Chandler et al.
patent: 7229406 (2007-06-01), Kehr et al.
patent: 2002/0029032 (2002-03-01), Arkin
patent: 2002/0115922 (2002-08-01), Waner et al.
patent: 2002/0186921 (2002-12-01), Schumacher et al.
patent: 2003/0060718 (2003-03-01), Alam et al.
patent: 2003/0212324 (2003-11-01), Knapp et al.
patent: 2004/0101822 (2004-05-01), Wiesner et al.
patent: 2004/0190975 (2004-09-01), Goodman et al.
patent: 2004/0225216 (2004-11-01), Zappala et al.
patent: 2004/0241148 (2004-12-01), Bellomo et al.
patent: 2005/0096509 (2005-05-01), Olson
patent: 2005/0182318 (2005-08-01), Kaji et al.
patent: 2005/0192480 (2005-09-01), Toriya et al.
patent: 2005/0277810 (2005-12-01), Irion
patent: 2006/0029802 (2006-02-01), Ying et al.
patent: 2006/0089570 (2006-04-01), Mansour et al.
patent: 2006/0159619 (2006-07-01), Becker et al.
patent: 2006/0173362 (2006-08-01), Toms et al.
patent: 2006/0183246 (2006-08-01), Wiesner et al.
patent: 2006/0228554 (2006-10-01), Tan et al.
patent: 2006/0245971 (2006-11-01), Burns et al.
patent: 2007/0016075 (2007-01-01), Takeda et al.
patent: 2007/0059705 (2007-03-01), Lu et al.
patent: 2007/0258908 (2007-11-01), Lanza et al.
patent: 2007/0260138 (2007-11-01), Feldman et al.
patent: 2008/0071208 (2008-03-01), Voegele et al.
patent: 2008/0154102 (2008-06-01), Frangioni et al.
patent: 2008/0213189 (2008-09-01), Lee et al.
patent: 2008/0226562 (2008-09-01), Groves et al.
patent: 2008/0234566 (2008-09-01), Voegele et al.
patent: 2008/0255403 (2008-10-01), Voegele et al.
patent: 2008/0255425 (2008-10-01), Voegele et al.
patent: 2008/0255459 (2008-10-01), Voegele et al.
patent: 2008/0255460 (2008-10-01), Voegele et al.
patent: 2008/0255537 (2008-10-01), Voegele et al.
patent: 2008/0319307 (2008-12-01), Voegele et al.
patent: 2009/0054761 (2009-02-01), Voegele et al.
patent: 2010/0015607 (2010-01-01), Geiss et al.
patent: 102005041271 (2007-03-01), None
patent: 1310206 (2003-05-01), None
patent: 1759628 (2007-03-01), None
patent: 10043205 (1998-02-01), None
patent: 2233611 (2004-08-01), None
patent: WO-02051302 (2002-07-01), None
patent: WO-2004045649 (2004-06-01), None
patent: WO-2004108902 (2004-12-01), None
patent: WO-2006086578 (2006-08-01), None
patent: WO-2006102307 (2006-09-01), None
patent: WO-2006110733 (2006-10-01), None
patent: WO-2007022196 (2007-02-01), None
patent: WO-2008127880 (2008-10-01), None
“Quantum Dots Could Guide Surgeons”, NIBIB, Feb. 11, 2004.
Ballou, B. et al., “Sentinel Lymph Node Imaging Using Quantum Dots in Mouse Tumor Models,” Bioconjugate Chem., 2007, 18 (2), pp. 389-396.
International Search Report mailed Sep. 14, 2010 for App. No. PCT/US2008/060045 (16 pages).
Lu, C. et al., “Bifunctional magnetic silica nanoparticles for highly efficient human stem cell labeling,” Nano Letters, Jan. 2007, vol. 7, No. 1, p. 149-154.
Yi, D. K. et al., “Silica-coated Nanocomposites of magnetic nanoparticles and quantum dots,” Journal of the American Chemical Society 20050413 US, vol. 127, No. 14, Apr. 13, 2005, p. 4990-4991.
Partial International Search Report, Annex to Form PCT/ISA/206, PCT/US2008/060045, Mailed Nov. 19, 2009, 10 pages.
Soltesz, E. et al., “Sentinel Lymph Node Mapping of the Gastrointestinal Tract by Using Invisible Light,” Annals of Surgical Oncology, vol. 13, No. 3, Mar. 1, 2006, pp. 386-396.
Szentkuti, L., “Light microscopial observations on luminally administered dyes, dextrans, nanospheres and microspheres in the pre-epithelial mucus gel layer of the rat distal colon,” Journal of Controlled Release, vol. 46, No. 3, Jun. 2, 1997, pp. 233-242.
Wang, L. et al., “Dual-Luminophore-Doped Silica Nanoparticles for Multiplexed Signaling,” Nano Letters, Jan. 2005, vol. 5, No. 1, pp. 37-43.
Yezhelyev, M. et al., “Emerging use of nanoparticles in diagnosis and treatment of breast cancer,” Lancet Oncology, Lancet Publishing Group, vol. 7, No. 8, Aug. 2006, pp. 657-667.
Levy, L. et al., “Nanochemistry: synthesis and characterization of multifunctional nanoclinics for biological application,” 2002 Chem. Mater. 14: 3715-3721.
Wang, L. et al., “Multicolor FRET silica nanoparticles by single wavelength excitation,” 2006 Nano Lett. 6: 84-88, Epub Dec. 20, 2005.
Xu, C. et al., “Dopamine as a robust anchor to immobilize functional molecules on the iron oxide shell of magnetic nanoparticles,” 2004 J. Am. Chem. Soc. 126: 9938-9939.
Troy et al., “Quantitative comparison of the sensitivity of detection of fluorescent and bioluminescent reporters in animal models,” 2004 Mol. Imaging 3: 9-23.

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