Synthesis of FR901464 and analogs with antitumor activity

Details Synthesis of FR901464 and analogs with antitumor activity Synthesis of FR901464 and analogs with antitumor activity

2007-09-08

2010-11-02

Andres, Janet L. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C549S419000, C514S456000

Reexamination Certificate

active

07825267

ABSTRACT:
The present invention provides novel analogs of FR901464, as well as an improved methodology for preparing FR901464 and its analogs. These compounds display an anti-cancer activity and are candidates for therapies against a number of disease states associated with dysfunctional RNA splicing.

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