Diagnostic test kits with improved detection accuracy

Details Diagnostic test kits with improved detection accuracy Diagnostic test kits with improved detection accuracy

2005-08-31

2010-11-09

Nguyen, Bao-Thuy L (Department: 1641)

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

C436S514000, C436S512000, C436S513000, C436S531000, C436S526000, C436S533000, C436S538000, C436S806000, C436S824000, C435S002000, C435S005000, C435S287200, C435S287900, C435S803000, C435S805000, C435S970000, C422S051000, C422S051000, C422S067000

Reexamination Certificate

active

07829347

ABSTRACT:
A diagnostic test kit that provides an integrated system for accurately detecting a test analyte over a broad range of possible concentrations is provided. One feature of the integrated system is that it is capable of indicating whether an analyte is within the “hook effect” region. Based on this indication, a technique may be selected for correlating a measured signal intensity to an analyte concentration or range of concentrations. For example, when it is determined that the test sample falls outside the “hook effect” region, the analyte concentration may be determined using one portion of a dose response curve. On the other hand, when it is determined that the test sample falls within the “hook effect” concentration, the analyte concentration may be determined using another portion of the dose response curve. Alternatively, the sample may simply be diluted for re-performing the assay. Regardless of whether the test sample is within or outside of the “hook effect” concentration, another feature of the integrated detection system of the present invention is that it is internally calibrated to provide a more accurate quantitative or semi-quantitative result to a user.

REFERENCES:
patent: 4168146 (1979-09-01), Grubb et al.
patent: 4235601 (1980-11-01), Deutsch et al.
patent: 4366241 (1982-12-01), Tom et al.
patent: 4385126 (1983-05-01), Chen et al.
patent: 4435504 (1984-03-01), Zuk et al.
patent: 4442204 (1984-04-01), Greenquist et al.
patent: 4540659 (1985-09-01), Litman et al.
patent: 4614723 (1986-09-01), Schmidt et al.
patent: 4742011 (1988-05-01), Blake et al.
patent: 4743542 (1988-05-01), Graham, Jr. et al.
patent: 4743560 (1988-05-01), Campbell et al.
patent: 4806312 (1989-02-01), Greenquist
patent: 4835099 (1989-05-01), Mize et al.
patent: 4843000 (1989-06-01), Litman et al.
patent: 4889816 (1989-12-01), Davis et al.
patent: 4904583 (1990-02-01), Mapes et al.
patent: 4920046 (1990-04-01), McFarland et al.
patent: 4954435 (1990-09-01), Krauth
patent: 4956302 (1990-09-01), Gordon et al.
patent: 4978625 (1990-12-01), Wagner et al.
patent: 4980298 (1990-12-01), Blake et al.
patent: 5028535 (1991-07-01), Buechler et al.
patent: 5073340 (1991-12-01), Covington et al.
patent: 5075077 (1991-12-01), Durley, III et al.
patent: 5075078 (1991-12-01), Osikowicz et al.
patent: 5089391 (1992-02-01), Buechler et al.
patent: 5120643 (1992-06-01), Ching et al.
patent: 5149622 (1992-09-01), Brown et al.
patent: 5185127 (1993-02-01), Vonk
patent: 5208143 (1993-05-01), Henderson et al.
patent: 5208535 (1993-05-01), Nakayama et al.
patent: 5252459 (1993-10-01), Tarcha et al.
patent: 5275785 (1994-01-01), May et al.
patent: 5387503 (1995-02-01), Selmer et al.
patent: 5395754 (1995-03-01), Lambotte et al.
patent: 5428690 (1995-06-01), Bacus et al.
patent: 5464741 (1995-11-01), Hendrix
patent: 5518883 (1996-05-01), Soini
patent: 5573909 (1996-11-01), Singer et al.
patent: 5573919 (1996-11-01), Kearns et al.
patent: 5585279 (1996-12-01), Davidson
patent: 5591581 (1997-01-01), Massey et al.
patent: 5591645 (1997-01-01), Rosenstein
patent: 5602040 (1997-02-01), May et al.
patent: 5610077 (1997-03-01), Davis et al.
patent: 5622871 (1997-04-01), May et al.
patent: 5637509 (1997-06-01), Hemilä et al.
patent: 5656503 (1997-08-01), May et al.
patent: 5670381 (1997-09-01), Jou et al.
patent: 5714389 (1998-02-01), Charlton et al.
patent: 5731147 (1998-03-01), Bard et al.
patent: 5788863 (1998-08-01), Milunic
patent: 5798273 (1998-08-01), Shuler et al.
patent: 5856203 (1999-01-01), Robinson et al.
patent: 5922537 (1999-07-01), Ewart et al.
patent: 5945281 (1999-08-01), Prabhu
patent: 5968839 (1999-10-01), Blatt et al.
patent: 5989924 (1999-11-01), Root et al.
patent: 5989926 (1999-11-01), Badley et al.
patent: 5998221 (1999-12-01), Malick et al.
patent: 6004530 (1999-12-01), Sagner et al.
patent: 6027944 (2000-02-01), Robinson et al.
patent: 6030840 (2000-02-01), Mullinax et al.
patent: 6057165 (2000-05-01), Mansour
patent: 6077669 (2000-06-01), Little et al.
patent: 6103536 (2000-08-01), Geisberg
patent: 6121008 (2000-09-01), Fitzpatrick et al.
patent: 6130100 (2000-10-01), Jobling et al.
patent: 6133048 (2000-10-01), Penfold et al.
patent: 6156271 (2000-12-01), May
patent: 6183972 (2001-02-01), Kuo et al.
patent: 6187269 (2001-02-01), Lancesseru et al.
patent: 6194220 (2001-02-01), Malick et al.
patent: 6242268 (2001-06-01), Wieder et al.
patent: 6261779 (2001-07-01), Barbera-Guillem et al.
patent: 6274324 (2001-08-01), Davis et al.
patent: 6294391 (2001-09-01), Badley et al.
patent: 6352862 (2002-03-01), Davis et al.
patent: 6362011 (2002-03-01), Massey et al.
patent: 6368875 (2002-04-01), Geisberg
patent: 6399398 (2002-06-01), Cunningham et al.
patent: 6436651 (2002-08-01), Everhart et al.
patent: 6444423 (2002-09-01), Meade et al.
patent: 6468741 (2002-10-01), Massey et al.
patent: 6509196 (2003-01-01), Brooks et al.
patent: 6524864 (2003-02-01), Fernandez Decastro
patent: 6582930 (2003-06-01), Ponomarev et al.
patent: 6585939 (2003-07-01), Dapprich
patent: 6613583 (2003-09-01), Richter et al.
patent: 6627459 (2003-09-01), Tung et al.
patent: 6653149 (2003-11-01), Tung et al.
patent: 6669908 (2003-12-01), Weyker et al.
patent: RE38430 (2004-02-01), Rosenstein
patent: 6893880 (2005-05-01), Carpenter
patent: 6951631 (2005-10-01), Catt et al.
patent: 7044919 (2006-05-01), Catt et al.
patent: 7052831 (2006-05-01), Fletcher et al.
patent: 2002/0042149 (2002-04-01), Butlin et al.
patent: 2002/0045273 (2002-04-01), Butlin et al.
patent: 2003/0002110 (2003-01-01), Schemmann et al.
patent: 2003/0100128 (2003-05-01), Kenjyou et al.
patent: 2003/0119202 (2003-06-01), Kaylor et al.
patent: 2003/0119204 (2003-06-01), Wei et al.
patent: 2003/0124739 (2003-07-01), Song et al.
patent: 2004/0029177 (2004-02-01), Nadaoka et al.
patent: 2004/0043502 (2004-03-01), Song et al.
patent: 2004/0043507 (2004-03-01), Song et al.
patent: 2004/0043511 (2004-03-01), Song et al.
patent: 2004/0106190 (2004-06-01), Yang et al.
patent: 2004/0121334 (2004-06-01), Wei et al.
patent: 2004/0121480 (2004-06-01), Wei et al.
patent: 2004/0151632 (2004-08-01), Badley et al.
patent: 2004/0161859 (2004-08-01), Guo et al.
patent: 2004/0197820 (2004-10-01), Wei et al.
patent: 2004/0235189 (2004-11-01), Lu
patent: 2004/0241700 (2004-12-01), Lamont et al.
patent: 2005/0029924 (2005-02-01), Okay et al.
patent: 2005/0036148 (2005-02-01), Phelan et al.
patent: 2005/0037510 (2005-02-01), Sharrock et al.
patent: 2005/0048599 (2005-03-01), Goldberg et al.
patent: 2005/0107956 (2005-05-01), Fukunaga et al.
patent: 2005/0109951 (2005-05-01), Fish et al.
patent: 2005/0112703 (2005-05-01), Song
patent: 2005/0112779 (2005-05-01), Wei et al.
patent: 2005/0112780 (2005-05-01), Song
patent: 2005/0136529 (2005-06-01), Yang et al.
patent: 2005/0243321 (2005-11-01), Cohen et al.
patent: 2006/0003390 (2006-01-01), Schaffler et al.
patent: 2006/0246522 (2006-11-01), Bhullar et al.
patent: 7 59407 (2000-02-01), None
patent: 0253464 (1988-01-01), None
patent: 1219964 (2002-07-01), None
patent: 1 491892 (2004-12-01), None
patent: WO 97/09620 (1997-03-01), None
patent: WO 2004 034056 (2004-04-01), None
patent: WO 2004 034056 (2004-04-01), None
U.S. Appl. No. 11/094,498, filed Mar. 30, 2005, Song et al., Diagnostic Test Kits Employing an Internal Calibration System.
U.S. Appl. No. 11/119,262, filed Apr. 29, 2005, Song et al., Assay Devices Having Detection Capabilities Within the Hook Effect Region.
International Search Report and Written Opinion dated Nov. 29, 2006 for Int'l Application No. PCT/US2006/016756.
Search Report and Written Opinion for PCT/US2006/002252, Jun. 29, 2006.

Affiliated with

Also associated with

Rating

Diagnostic test kits with improved detection accuracy does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Diagnostic test kits with improved detection accuracy, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Diagnostic test kits with improved detection accuracy will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4250730