Transposase and method of gene modification

Details Transposase and method of gene modification Transposase and method of gene modification

2006-03-14

2010-06-22

Chen, Shin-Lin (Department: 1632)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S002600, C536S023100, C530S350000, C435S320100, C435S455000

Reexamination Certificate

active

07741302

ABSTRACT:
A transposase encoded by the Tol2 element; a polynucleotide encoding the same; a method of modifying the gene structure of a cell (preferably a vertebrate cell) by using the above protein; a method of modifying the function of a cell by modifying the gene structure thereof; and a cell having been modified in function by these methods. Also the structure of a cis element necessary in gene transfer is clarified and presented.

REFERENCES:
patent: 7034115 (2006-04-01), Kawakami
patent: 2006/0211116 (2006-09-01), Kawakami
patent: 2006/0212958 (2006-09-01), Kawakami
Kawakami et al., Nov. 1999, GenEmbl Accession No. AB032244, pp. 1-3.
SPTREMBL Accession Nos. Q98968, 98969, 98970, and 98971, 1997, pp. 3-4.
Ivics et al., 1997, Cell, vol. 91, p. 501-510.
Kawakami et al., 2000, UniProt, Accession No. Q9PVN3, computer printout, p. 2-3.
Atkinson et al., 1993, PNAS, vol. 90, pp. 9693-9697.
K. Kawakami et al.,Gene, 240: 239-244 (1999).
K. Kawakami et al.,Gene, 225: 17-22 (1998).
A. Koga et al.,Genbank, Acc. No. D84375 (1999).
A. Koga et al.,FEBS Letters, 461: 295-298 (1999).
A Koga et al.,Nature, 383: 30 (1996).
G. Luo,Proc. Natl. Acad. Sci. USA, 95: 10769-10773 (1998).
L. Zhang et al.,Nucleic Acids Research, 26 (16): 3687-3693 (1998).
A. Sherman et al,Nature Biotechnology, 16:1050-1053 (1998).
Z. Li et al.,Somatic Cell and Molecular Genetics, 24(6): 363-369 (1998).
E. Rubin et al,Proc. Natl. Acad. Sci USA, 96: 1645-1650 (1999).
K. Kawakami et al.,Gene, 240: 239-244 (1999), Databse accession No. AB032244 (abstract only).
A. Koga et al.,Nature, 383: 30-30 (1996), Database accession No. Q98969 (abstract only).
Izsvak et al.,Biochemistry&Cell Biology, 75: 507-523 (1997).
GenEmbl Accession No. AB032244, Nov. 26, 1999, pp. 1-3.
SPTREMBL Accession Nos. Q98968, 98969, 98970, 98971, 1997, pp. 3-4.
Rudinger, 1976, Peptide Hormones, Parsons, University Park Press, Baltimore. p. 1-7.
Kaye et al., 1990, Proc. Natl. Acad. Sci. USA, vol. 87, pp. 6922-6926.
Skolnick et al., 2000, Trends in Biotech, vol. 18, pp. 34-39.
De Lorenzo, Victor, “Genetic Engineering Strategies for Environmental Applications,” Current Opinion in Biotechnology, 3(3): 227-231 (1992).
Lewin, B., “Genes VI”, Chapter 18, p. 564 (Oxford University Press 1997) (excerpt).
Lander, E.S., et al., “Initial sequencing and analysis of the human genome”, Nature, 409(6822):860-921 (2001) (excerpt).
Ivics, Z., et al., “Molecular Reconstruction of Sleeping Beauty, a Tc1-like Transposon from Fish, and Its Transposition in Human Cells”, Cell, vol. 91, 501-510 (1997) (excerpt).
Kunze et al., “Transcription of transposable elementActivator(Ac) ofZea maysL.,” The EMBO Journal, vol. 6, No. 6, pp. 1555-1563 (1987).
Izsvak et al., “Short Inverted-Repeat Transposable Elements in Teleost Fish and Implications for a Mechanism of Their Amplification,” Journal of Molecular Evolution, vol. 48, pp. 13-21, (Jan. 1999).

Affiliated with

Also associated with

Rating

Transposase and method of gene modification does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Transposase and method of gene modification, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Transposase and method of gene modification will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4247746