Metal complexes based on tetrathiol ligands and their use in...

Details Metal complexes based on tetrathiol ligands and their use in... Metal complexes based on tetrathiol ligands and their use in...

2005-04-28

2010-06-08

Shiao, Rei-tsang (Department: 1628)

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

C534S014000, C534S010000

Reexamination Certificate

active

07731936

ABSTRACT:
Provided are radiolytically and metabolically stable metal complexes based on tetrathiol ligands useful for nuclear medical diagnostics and in endoradionuclide therapy. Methods for their preparation are also provided. The complexes can have a central ligand, Y, that can be99mTcO,186ReO,188ReO,99mTcN,186ReN or188ReN.

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Anderson et al., CAS: 148:375578.
Jan. 1, 2003 New routes to bioconjugates of rhenium using the oxobis(dithiolato)rhenate(v)core Uzma Choudhry et al. The Royal Society of Chemistry pp. 311-317.
Jul. 19, 2000 Simple New Method for Effective Concentration of I88Re Solutions from Alumina-Based 188W-188Re Generator Stefan Guhlke et al. The Journal of Nuclear Medicine vol. 41, No. 7 pp. 1271-1278.

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