Actuable structures and methods of fabrication and use

Surgery – Instruments – Surgical mesh – connector – clip – clamp or band

Reexamination Certificate

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C623S014130, C623S917000, C623S918000, C623S919000

Reexamination Certificate

active

07811297

ABSTRACT:
An actuable truss with ordered or disordered planar or strut elements or pore walls may be seeded with tissue cells, wherein application of a magnetic field may result in mechanical strain on the cells and increased fluid flow in and out of the truss structure. Modified polymers, such as γ-Fe2O3/PLGA, may be used to form actuable scaffolds suitable for tissue engineering. It is also disclosed a device with a trap-door that may be remotely actuated by applying a magnetic field. Such a device may be employed to deliver and control the release of other micro-devices or materials such as drugs to a specific location inside the body of a human or an animal.

REFERENCES:
patent: 4032929 (1977-06-01), Fischbeck et al.
patent: 2004/0098042 (2004-05-01), Devellian et al.
patent: 2004/0136905 (2004-07-01), Kent et al.
patent: 2005/0245658 (2005-11-01), Mehrotra et al.
Stankus et al.; Microintegrating smooth muscle cells into a biodegradable elastomeric fiber matrix, Biomaterials 2006;27:735-744.
Stitzel, et al.; Controlled Fabrication of a Biological Vascular Substitute, Biomaterials 2006;27:1088-1094.
Wang, et al.; Precision Extruding Deposition and Characterization of Cellular Poly-∈-caprolactone tissue scaffolds 2004;10(1):42-49.

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